Database : HANSEN Search on : COMPLEXO ANTIGENO-ANTICORPO [Subject descriptor] References found : 24 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 13544 Author: Convit, Jacinto; Ulrich, Marian Title: Recent advances in the immunology of leprosy ..- Source: s.l; s.n; apr. 1976. 14 p. ilus. Abstract: For many decades, interest in leprosy has been largely limited to those areas of the tropical and subtropical world where the disease constitutes an important public health problem.(AU). Descriptors: ANTICORPOS ANTIBACTERIAS COMPLEXO ANTIGENO-ANTICORPO REACOES ANTIGENO-ANTICORPO TECNICAS IMUNOLOGICAS HANSENIASE/quimioter HANSENIASE/imunol HANSENIASE/patol LINFOCITOS/imunol MACROFAGOS/imunol MYCOBACTERIUM LEPRAE/imunol - IMUNIZACAO PASSIVA  SINDROMES DE DEFICIÊNCIA IMUNOLOGICA/imunol  IMUNOTERAPIA  VACINACAO  IMUNIDADE  IMUNIDADE CELULAR  TATUS/imunol  MODELOS ANIMAIS DE DOENCAS Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 00578/s

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Id: 13539 Author: Ramanathan, V. D; Thyagi, P; Ramanathan, U; Katoch, K; Ramu, G Title: A sequential study of circulating immune complexes, complement and immunoglobulins in borderline tuberculoid leprosy patients with and without reactions ..- Source: s.l; s.n; 1998. 8 p. tab, graf. Abstract: Sequential estimates of the levels of circulating immune complexes (CIC), complement catabolic fragment C3d, complement-mediated immune complex solubilization (CMS) and immunoglobulins were made in 24 newly diagnosed with borderline tuberculoid leprosy over a 20 month period after initiation of chemotherapy. Fourteen of these patients had not suffered from reversal reactions either at the time of presentation or during the follow-up. The levels of CIC were evaluated in them from the third to the eleventh month after starting chemotherapy and immunoglobulin G (IgG) levels were evaluated up to eight months. The concentrations of C3d and immunoglobulins A (IgA) and M (IgM) were normal in these patients. The other ten patients had reversal reaction at the time of diagnosis which subsided by the third month after starting treatment. They did not have reversal reactions later. The levels of CIC and IgG were elevated and those of CMS were depressed throughout the study period. Serum C3d level was initially elevated but came down to normal by the third month while IgA and IgM levels were within normal limits. The relevance of these findings to the genesis of reversal reaction is discussed in this communication.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO/sangue COMPLEMENTO 3D/anal ANTIGENO DE MITSUDA IMUNOGLOBULINAS/sangue HANSENOSTATICOS/uso terap HANSENIASE TUBERCULOIDE/quimioter HANSENIASE TUBERCULOIDE/imunol FATORES DE TEMPO Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE Location: BR191.1; 09164/s

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Id: 13451 Author: Young, Douglas B; Khanolkar, Saroj R; Barg, Linda L; Buchanan, Thomas M Title: Generation and characterization of monoclonal antibodies to the phenolic glycolipid of Mycobacterium leprae ..- Source: s.l; s.n; jan. 1984. 6 p. ilus, tab, graf. Abstract: Nine cloned cell lines producing antibodies to the unique phenolic glycolipid of Mycobacterium leprae have been established as a result of fusions with spleens from mice immunized with the glycolipid complexed with methylated bovine serum albumin. One of the antibodies was relatively nonspecific, binding to a related glycolipid from Mycobacterium kansasii, but the remaining antibodies were specific for the M. leprae lipid. Some of the antibodies required the intact (trisaccharide) carbohydrate portion for recognition of the glycolipid antigen, whereas others recognized partially hydrolyzed forms lacking one or two sugar residues. Monoclonal antibodies directed at the terminal saccharide of the glycolipid showed the greatest specificity for M. leprae in enzyme-linked immunoassays. These antibodies brightly labeled whole mycobacteria in indirect immunofluorescence experiments, demonstrating the surface location of M. leprae-specific determinants of the glycolipid antigen. In addition to their use in providing information about the antigenic properties of the phenolic glycolipid, these antibodies have potential applications for elucidating the roles of glycolipid in the pathogenesis of leprosy.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO ELISA IMUNOFLUORESCÊNCIA GLICOLIPIDIOS/anal GLICOLIPIDIOS/imunol MYCOBACTERIUM LEPRAE CAMUNDONGOS ENDOGÂMICOS BALB C FENOIS PLASMOCITOMA/imunol ESPECIFICIDADE DE ESPECIES Limits: ESTUDO COMPARATIVO ANIMAL CAMUNDONGOS SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 01417/s

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Id: 13435 Author: Wing Ling, Ng; Scollard, David M; Hua, Andrew Title: Glomerulonephritis in leprosy ..- Source: s.l; s.n; sep. 1981. 9 p. ilus, tab. Abstract: A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO BIOPSIA ERITEMA NODOSO DOENCAS DO COMPLEXO IMUNE/imunol GLOMERULONEFRITE/compl GLOMERULONEFRITE/imunol HANSENIASE/compl RIM/patol Limits: RELATO DE CASO HUMANO MASCULINO MEIA-IDADE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01782/s

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Id: 13417 Author: Bjorvatn, B; Barnetson, R. S; Kronvall, G; Zubler, R. H; Lambert, P. H Title: Immune complexes and complement hypercatabolism in patients with leprosy ..- Source: s.l; s.n; dec. 1976. 9 p. tab, graf. Abstract: The occurrence of immune complexes in the serum and the level of the C3 breakdown product C3d in the plasma from patients with leprosy were studied by quantitative methods and the results were compared in various forms of the disease. These studies were performed on sixty-two samples from twenty-six patients. The serum 125I-C1q binding activity was found to be increased by more than 2 s.d., as compared to the normal values, in most of the sera from patients with erythema nodosum leprosum (ENL) (80%) and uncomplicated lepromatous leprosy (82%), but also in the sera from patients with tuberculoid leprosy (58%). In vitro studies suggested that immune complexes involving mycobacterial antigens were present in leprosy sera. An increased C3d level (greater than 2s.d.) was also found in most of the plasma from patients with ENL (70%), but rarely in the plasma from patients with uncomplicated lepromatous leprosy (18%) and never in tuberculoid leprosy patients' plasma. The absence of a significant correlation between the 125I-C1q binding activity and the C3d level in leprosy patients may suggest that extravascular immune complexes are involved in the complement activation occurring in ENL. The quantitation of C3d in plasma may be of some practical interest in the early diagnosis of ENL complications of leprosy.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO COMPLEMENTO 1/metab COMPLEMENTO 3/metab TESTES DE FIXACAO DE COMPLEMENTO ERITEMA NODOSO/imunol HANSENIASE/imunol Limits: HUMANO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 00016/s

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Id: 13363 Author: Ng, Wing Ling; Scollard, David M; Hua, Andrew Title: Glomerulonephritis in leprosy ..- Source: s.l; s.n; sep. 1981. 9 p. ilus, tab. Abstract: A renal biopsy from a patient with lepromatous leprosy but no history of erythrema nodosum leprosum (ENL) showed histologic, immunofluorescent, and ultrastructural features typical of immune-complex glomerulonephritis. A literature review found reports of 187 renal biopsies from leprosy patients, with glomerulonephritis in 31% of the cases, and a variety of other renal lesions. This accumulated evidence demonstrates that, contrary to widely held opinion, there is no association between glomerulonephritis and a history of ENL. Furthermore, it suggests that glomerulonephritis in leprosy patients has a similar incidence in lepromatous and non-lepromatous cases. These observations have an important bearing on concepts regarding the pathogenesis of immune complex glomerulonephritis in leprosy and the humoral immune mechanisms in patients with leprosy.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO BIOPSIA ERITEMA NODOSO DOENCAS DO COMPLEXO IMUNE/imunol RIM/patol HANSENIASE/compl GLOMERULONEFRITE/compl GLOMERULONEFRITE/imunol Limits: RELATO DE CASO HUMANO MASCULINO MEIA-IDADE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01938/s

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Id: 13351 Author: Moran, C. J; Ryder, G; Turk, J. L; Waters, M. F Title: Evidence for circulating immune complexes in lepromatous leprosy ..- Source: s.l; s.n; September 16, 1972. 2 p. tab. Abstract: Sera from patients with lepromatous leprosy react with the Clq component of complement in vitro. The incidence of sera that react in this way is higher in patients with active erythema nodosum leprosum (E.N.L.). This is further, although circumstantial, evidence for the immune complex aetiology of E.N.L. and opens a way for the more precise identification of the antigen involved.(AU). Descriptors: COMPLEMENTO ERITEMA NODOSO/imunol SOROS IMUNES HANSENIASE/imunol TESTES DE PRECIPITINA PROGNOSTICO COELHOS/imunol COMPLEXO ANTIGENO-ANTICORPO Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 01835/s

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Id: 13350 Author: Bjorvatn, B; Barnetson, R. S; Kronvall, G; Zubler, R. H; Lambert, P. H Title: Immune complexes and complement hypercatabolism in patients with leprosy ..- Source: s.l; s.n; dec. 1976. 9 p. tab, graf. Abstract: The occurrence of immune complexes in the serum and the level of the C3 breakdown product C3d in the plasma from patients with leprosy were studied by quantitative methods and the results were compared in various forms of the disease. These studies were performed on sixty-two samples from twenty-six patients. The serum 125I-C1q binding activity was found to be increased by more than 2 s.d., as compared to the normal values, in most of the sera from patients with erythema nodosum leprosum (ENL) (80%) and uncomplicated lepromatous leprosy (82%), but also in the sera from patients with tuberculoid leprosy (58%). In vitro studies suggested that immune complexes involving mycobacterial antigens were present in leprosy sera. An increased C3d level (greater than 2s.d.) was also found in most of the plasma from patients with ENL (70%), but rarely in the plasma from patients with uncomplicated lepromatous leprosy (18%) and never in tuberculoid leprosy patients' plasma. The absence of a significant correlation between the 125I-C1q binding activity and the C3d level in leprosy patients may suggest that extravascular immune complexes are involved in the complement activation occurring in ENL. The quantitation of C3d in plasma may be of some practical interest in the early diagnosis of ENL complications of leprosy.(AU). Descriptors: COMPLEMENTO 3/metab TESTES DE FIXACAO DE COMPLEMENTO ERITEMA NODOSO/imunol HANSENIASE/imunol COMPLEMENTO 1/metab COMPLEXO ANTIGENO-ANTICORPO Limits: HUMANO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01833/s

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Id: 13336 Author: Valentijn, R. M; Faber, W. R; Lai A Fat, R. F; Chan Pin Jie, J. C; Daha, M. R; van Es, L. A Title: Immune complexes in leprosy patients from an endemic and a nonendemic area and a longitudinal study of the relationship between complement breakdown products and the clinical activity of erythema nodosum leprosum ..- Source: s.l; s.n; feb. 1982. 8 p. tab, graf. Abstract: The sera from leprosy patients living in Surinam (endemic) and 41 leprosy patients living in The Netherlands (nonendemic) were tested for circulating immune complexes (CIC) with the Clq-binding assay and the conglutinin-binding assay and for complement.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO/anal COMPLEMENTO 1Q COMPLEMENTO 3/anal ENZIMAS ATIVADORAS DO COMPLEMENTO/metab ERITEMA NODOSO/epidemiol ERITEMA NODOSO/imunol HANSENIASE/clas HANSENIASE/epidemiol HANSENIASE/imunol - COMPLEMENTO/anal  ESTUDOS LONGITUDINAIS  SURINAME  PAISES BAIXOS Limits: HUMANO MASCULINO FEMININO SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 01133/s

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Id: 13334 Author: Geniteau, M; Adam, C; Verroust, P; Pasticier, A; Saimot, G; Coulaud, J. P; Languillon, J Title: Les complexes immuns et le complément dans la lèpre Immune complexes and complement in leprosy- Source: s.l; s.n; Dec. 1981. 4 p. tab, graf. Abstract: The sera of 87 Senegalese patients with various forms of leprosy were investigated. Two of the most reliable methods were used to detect circulating immune complexes : the radiolabelled C1q binding test and the Raji cell binding technique. Several fractions of complement, including C3, C4, factor B and the C3d product of C3 were also assayed. A material having the properties of immune complexes was detected in lepromatous and reactional leprosy. In tuberculous leprosy, only the Raji cell binding technique gave positive results. C3 and C4 were normal or slightly raised, but C3d was increased in all forms of the disease. There was no significant correlation between C3d values and the results of immune complexes detection tests.(AU). Descriptors: COMPLEMENTO 4/anal COMPLEMENTO 3/anal COMPLEXO ANTIGENO-ANTICORPO/anal HANSENIASE/imunol - SENEGAL Limits: HUMANO RESUMO EM INGLES Electronic Medium: http://www.ilsl.br Location: BR191.1; 01123/s

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Id: 13331 Author: Furukawa, F; Sekita, K; Hamashima, Y; Ozaki, M; Imamura, S Title: Evaluation of circulating immune complexes and antinuclear antibodies in japanese patients with leprosy ..- Source: s.l; s.n; 1983. 3 p. tab, graf. Abstract: In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found....(AU). Descriptors: HANSENIASE/imunol COMPLEXO ANTIGENO-ANTICORPO/anal ANTICORPOS ANTINUCLEARES/anal ANTICORPOS ANTINUCLEARES/genet - FENOTIPO  RADIOIMUNOENSAIO Electronic Medium: http://www.ilsl.br Location: BR191.1; 01236/s

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Id: 13325 Author: Moran, C. J; Ryder, G; Turk, J. L; Waters, M. F. R Title: Evidence for circulating immune complexes in lepromatous leprosy ..- Source: s.l; s.n; sep. 1972. 2 p. tab. Abstract: Sera from patients with lepromatous leprosy react with the Clq component of complement in vitro. The incidence of sera that react in this way is higher in patients with active erythema nodosum leprosum. (AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO COMPLEMENTO ERITEMA NODOSO/imunol SOROS IMUNES HANSENIASE/imunol TESTES DE PRECIPITINA PROGNOSTICO COELHOS/imunol Limits: HUMANO ANIMAL Electronic Medium: http://www.ilsl.br Location: BR191.1; 01272/s

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Id: 13314 Author: Tung, K. S; Kim, B; Bjorvatn, B; Kronvall, G; McLaren, L. C; Williams, R. C Title: Discrepancy between Clq deviation and Raji cell tests in detection of circulating immune complexes in patients with leprosy ..- Source: s.l; s.n; aug. 1977. 6 p. ilus, tab, graf. Abstract: Samples of serum from 45 patients with different clinical forms of leprosy and from 17 patients with systemic lupus erythematosus were studied in parallel for circulating immune complexes with use of two different in vitro tests adjusted to the same degree of sensitivity. The Clq deviation test relied upon the reaction of the complement component Clq with immune complexes. The Raji cell test detected complement-fixed immune complexes that bound to the complement receptors on cultured, bone marrow-derived lymphocyte-like Raji cells. Thirty (67%) of 45 patients with leprosy showed immune complexes according to the Clq deviation test; however, only two (7%) of the 30 samples of sera with positive Clq test results were positive by the Raji cell test. In contrast, 54% of 13 samples of sera from patients with systemic lupus erythematosus positive by the Clq test were positive according to the Raji cell test. Since Clq is known to react with DNA as well as with bacterial antigens, the Clq reaction may in fact be detecting antigenemia in many instances. Considerable caution is warranted in application of sensitive screening tests for assay of circulating immune complexes in various states of infectious diseases.(AU). Descriptors: HANSENIASE/imunol TECNICAS IMUNOLOGICAS DNA/imunol DNA/metab ANTICORPOS COMPLEXO ANTIGENO-ANTICORPO LINHAGEM CELULAR COMPLEMENTO/metab COMPLEMENTO 1/metab LUPUS ERITEMATOSO SISTÊMICO/imunol Limits: ESTUDO COMPARATIVO HUMANO SUPPORT, U.S. GOV'T, P.H.S. Electronic Medium: http://www.ilsl.br Location: BR191.1; 01271/s

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Id: 11296 Author: Rojas, R. E; Demichelis, S. O; Sarno, E. N; Segal-Eiras, A Title: IgM anti-phenolic glycolipid I and IgG anti 10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts ..- Source: s.l; s.n; 1997. 10 p. tab, graf. Descriptors: ADOLESCENCIA ANTICORPOS ANTIBACTÉRIAS ANTICORPOS ANTIBACTÉRIAS ANTICORPOS ANTIBACTÉRIAS ANTICORPOS MONOCLONAIS COMPLEXO ANTIGENO-ANTICORPO COMPLEXO ANTIGENO-ANTICORPO COMPLEXO ANTIGENO-ANTICORPO ANTIGENOS DE BACTÉRIAS CHAPERONINA 10 CHAPERONINA 10 ELISA ERITEMA NODOSO ERITEMA NODOSO GLICOLIPIDIOS IGG IGM HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA POLIETILENOGLICOIS PROTEINAS RECOMBINANTES Limits: ESTUDO COMPARATIVO Location: BR191.1; 07235/s

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Id: 11062 Author: Patil, Shripad A; Ramu, Gopal; Prasad, Rama Title: Detection of disease related immune complexes in the serum of leprosy patients a novel single step method ..- Source: s.l; s.n; 2000. 5 p. tab, graf. Descriptors: HANSENIASE COMPLEXO ANTIGENO-ANTICORPO MYCOBACTERIUM BOVIS NEURITE Location: BR191.1; 07446/s

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Id: 10196 Author: Rojas, R. E; Segal-Eiras, A Title: Characterization of circulating immune complexes in leprosy patients and their correlation with specific antibodies against Mycobacterium leprae ..- Source: s.l; s.n; 1997. 7 p. ilus, tab, graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE ANTICORPOS ANTIBACTÉRIAS ESPECIFICIDADE DE ANTICORPOS COMPLEXO ANTIGENO-ANTICORPO COMPLEXO ANTIGENO-ANTICORPO ELISA Location: BR191.1; 07129/s

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Id: 9734 Author: Corsico, B.; Croce, M. V.; Mukherjee, R; Segal-Eiras, A Title: Identification of myelin basic proteins in circulating immune complexes associated with lepromatous leprosy ..- Source: s.l; s.n; 1994. 6 p. ilus. Descriptors: HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA COMPLEXO ANTIGENO-ANTICORPO WESTERN BLOTTING ELETROFORESE EM GEL DE POLIACRILAMIDA PROTEINAS BASICAS DA MIELINA Limits: HUMANO Location: BR191.1; 06715/s

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Id: 9713 Author: Wang, Chrong-Reen; Liu, Ming-Fei; Jeng, Geng-Wang; Lin, Huan-Po; Hsieh, Rhong-Phong; Chuang, Che-Yen; Chang, Cheng-Erh Title: Autoantibodies and related immunity of leprosy patients from leprosarium in Taiwan ..- Source: s.l; s.n; 1992. 8 p. . Descriptors: COMPLEXO ANTIGENO-ANTICORPO AUTO-ANTICORPOS ELETROFORESE DAS PROTEINAS SANGUINEAS IMUNIDADE CELULAR HANSENIASE FORMOSA Location: BR191.1; 06511/s

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Id: 9659 Author: Vaishnavi, Chetana; Ganguly, Nirmal Kumar; Kaur, Surrinder; Kumar, Bhushan Title: Suppression of ADCC by immune complex formed in vitro in Mycobacterium leprae-infected mice ..- Source: s.l; s.n; 1993. 5 p. tab. Descriptors: HANSENIASE HANSENIASE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE CITOTOXICIDADE CELULAR ANTICORPO-DEPENDENTE COMPLEXO ANTIGENO-ANTICORPO CONTAGEM DE COLONIA MICROBIANA TOLERANCIA IMUNOLOGICA IMUNIDADE CELULAR FATORES DE TEMPO Limits: ANIMAL CAMUNDONGOS Location: BR191.1; 06544/s

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Id: 9455 Author: Laal, Suman; Sharma, Y. D; Prasad, H. K; Murtaza, Anwar; Singh, Satish; Tangri, Shabnam; Misra, Radhey; Nath, Indira Title: Recombinant fusion protein identified by lepromatous sera mimics native Mycobacterium leprae in T-cell responses across the leprosy spectrum ..- Source: s.l; s.n; 1991. 5 p. ilus, tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ANTICORPOS MONOCLONAIS ESPECIFICIDADE DE ANTICORPOS COMPLEXO ANTIGENO-ANTICORPO ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS SEQUENCIA DE BASES BIBLIOTECA DE GENES SOROS IMUNES IMMUNOBLOTTING HANSENIASE HANSENIASE LEPROMATOSA TRANSFORMAÇAO LINFOCITICA DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE PROTEINAS RECOMBINANTES DE FUSAO PROTEINAS RECOMBINANTES DE FUSAO VALORES DE REFERENCIA MAPEAMENTO POR RESTRIÇAO LINFOCITOS T Location: BR191.1; 06305/s

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